{"id":123,"date":"2026-05-28T10:43:55","date_gmt":"2026-05-28T10:43:55","guid":{"rendered":"https:\/\/www.ultraconecta.com\/ar\/?page_id=123"},"modified":"2026-09-18T09:11:49","modified_gmt":"2026-09-18T09:11:49","slug":"acerca-de-xlh","status":"publish","type":"page","link":"https:\/\/www.ultraconecta.com\/ar\/acerca-de-xlh\/","title":{"rendered":"Acerca de xlh"},"content":{"rendered":"<p>  <main><\/p>\n<p>        <!-- ============================================================\n             1. PAGE HERO \u2014 \"\u00bfQu\u00e9 es XLH?\" with image right\n             ============================================================ --><\/p>\n<section class=\"page-hero\">\n<div class=\"container\">\n<div class=\"page-hero__inner\">\n<div class=\"page-hero__content\">\n<h1 class=\"page-hero__title\">\u00bfQU\u00c9 ES XLH?<\/h1>\n<p class=\"page-hero__text\">\n          La hipofosfatemia ligada al cromosoma X (XLH) es una enfermedad poco<br \/>\n          frecuente que afecta a huesos, m\u00fasculos y dientes debido a la p\u00e9rdida<br \/>\n          excesiva de fosfato.\n        <\/p>\n<p class=\"page-hero__text\">\n          XLH no solo afecta en la ni\u00f1ez.  Una persona con XLH convivir\u00e1 con ella durante toda su<br \/>\n          vida.\n        <\/p>\n<\/p><\/div>\n<div class=\"page-hero__media\">\n        <img decoding=\"async\" fetchpriority=\"high\"\nwidth=\"1217\" height=\"362\"\n             src=\"\/ar\/wp-content\/uploads\/Naomi-convive-con-XLH.webp\"\n             alt=\"Paola y su hija Noemi, ambas pacientes XLH, sonriendo abrazadas\">\n      <\/div>\n<div class=\"page-hero__name\">\n<p>Paola y Naomi,<br \/>conviven con XLH<\/p>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/section>\n<p>        <!-- ============================================================\n             2. HEREDITARIA + CAROUSEL \u2014 Two-column section\n             ============================================================ --><\/p>\n<section class=\"info-split\">\n<div class=\"container\">\n<div class=\"content-wrap\">\n                <!-- Breadcrumb --><\/p>\n<nav class=\"breadcrumb\" aria-label=\"Migas de pan\">\n                    <a href=\"https:\/\/www.ultraconecta.com\/ar\/\">Inicio<\/a><br \/>\n                    <span class=\"breadcrumb__sep\">\/<\/span><br \/>\n                    <a href=\"#\">ACERCA DE XLH<\/a><br \/>\n                    <span class=\"breadcrumb__sep\">\/<\/span><br \/>\n                    <span class=\"breadcrumb__current\">\u00bfQu\u00e9 es XLH?<\/span><br \/>\n                <\/nav>\n<p>       <!-- ============================================================\n             NEW SECTION .  \u2014 Cyan band with alternate names\n             ============================================================ --><\/p>\n<section class=\"causes_one\">\n<div class=\"container\">\n<h2 class=\"section-heading section-head\">XLH tambi\u00e9n puede ser conocida como:<\/h2>\n<ul class=\"causes__list_one\">\n<li>Raquitismo hipofosfat\u00e9mico ligado al cromosoma X<\/li>\n<li>Raquitismo hipofosfat\u00e9mico hereditario<\/li>\n<li>Raquitismo hipofosfat\u00e9mico familiar<\/li>\n<li>Raquitismo hipofosfat\u00e9mico<\/li>\n<\/ul><\/div>\n<\/section>\n<p><!-- old --><\/p>\n<div class=\"info-split__grid\">\n<p>                    <!-- Left column: heading + text --><\/p>\n<div class=\"info-split__text\">\n<h3 class=\"section-heading section-line\">\u00bfCu\u00e1l es la causa de XLH?<\/h3>\n<p>\nLas personas con XLH tienen una mutaci\u00f3n en el <strong>gen PHEX,<\/strong> que hace que el organismo produzca demasiada cantidad de una hormona llamada factor de crecimiento de fibroblastos 23 (FGF23). El <strong>FGF23<\/strong> controla la cantidad de fosfato  presente en la sangre.\n                        <\/p>\n<p>\n                        En XLH, el fosfato se pierde a trav\u00e9s de la orina, lo que provoca niveles bajos<br \/>\n                         de f\u00f3sforo en la sangre, un trastorno denominado <strong>p\u00e9rdida de fosfato o<br \/>\n                         hipofosfatemia.<\/strong> El fosfato es una mol\u00e9cula necesaria para tener huesos,<br \/>\n                          m\u00fasculos y dientes sanos.\n                        <\/p>\n<p>\n                        La hipofosfatemia cr\u00f3nica hace que los huesos se vuelvan d\u00e9biles y blandos, provocando los s\u00edntomas de XLH.\n                        <\/p>\n<\/p><\/div>\n<p>                    <!-- Right column: working carousel --><\/p>\n<div class=\"info-split__carousel\">\n<div class=\"carousel\" id=\"infoCarousel\" aria-roledescription=\"carrusel\" aria-label=\"Informaci\u00f3n sobre XLH\">\n<p>                            <button class=\"carousel__btn carousel__btn--prev\" type=\"button\" aria-label=\"Anterior\"><br \/>\n                                <svg viewBox=\"0 0 36 36\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" aria-hidden=\"true\">\n                                    <path d=\"M3.6 18 L21.6 36 L25.2 32.4 L10.8 18 L25.2 3.6 L21.6 0 Z\" fill=\"#6D72A2\" fill-opacity=\"0.7\"\/>\n                                <\/svg><br \/>\n                            <\/button><\/p>\n<div class=\"carousel__viewport\">\n<ul class=\"carousel__track\" id=\"carouselTrack\">\n<li class=\"carousel__slide\" aria-roledescription=\"diapositiva\" aria-label=\"1 de 4\">\n<div class=\"carousel__visual\">\n                                            <img decoding=\"async\" src=\"https:\/\/www.ultraconecta.com\/ar\/wp-content\/uploads\/causa-de-xlh-1-1.png\" alt=\"\" width=\"382\" height=\"508\" class=\"alignnone size-full wp-image-358\" loading=\"lazy\"\nfetchpriority=\"low\"\/>                                    <\/li>\n<li class=\"carousel__slide\" aria-roledescription=\"diapositiva\" aria-label=\"2 de 4\">\n<div class=\"carousel__visual\">\n                                            <img decoding=\"async\" src=\"https:\/\/www.ultraconecta.com\/ar\/wp-content\/uploads\/causa-de-xlh-2-1.png\" alt=\"\" width=\"382\" height=\"508\" class=\"alignnone size-full wp-image-361\" loading=\"lazy\"\nfetchpriority=\"low\"\/><\/p><\/div>\n<\/li>\n<li class=\"carousel__slide\" aria-roledescription=\"diapositiva\" aria-label=\"3 de 4\">\n<div class=\"carousel__visual\">\n                                            <img decoding=\"async\" src=\"https:\/\/www.ultraconecta.com\/ar\/wp-content\/uploads\/causa-de-xlh-3-1.png\" alt=\"\" width=\"382\" height=\"508\" class=\"alignnone size-full wp-image-361\" loading=\"lazy\"\nfetchpriority=\"low\"\/>\n                                        <\/div>\n<\/li>\n<li class=\"carousel__slide\" aria-roledescription=\"diapositiva\" aria-label=\"4 de 4\">\n<div class=\"carousel__visual\">\n                                            <img decoding=\"async\" src=\"https:\/\/www.ultraconecta.com\/ar\/wp-content\/uploads\/causa-de-xlh-4-1.png\" alt=\"\" width=\"382\" height=\"508\" class=\"alignnone size-full wp-image-361\" loading=\"lazy\"\nfetchpriority=\"low\"\/>\n                                        <\/div>\n<\/li>\n<\/ul><\/div>\n<p>                            <button class=\"carousel__btn carousel__btn--next\" type=\"button\" aria-label=\"Siguiente\"><br \/>\n                                <svg viewBox=\"0 0 36 36\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" aria-hidden=\"true\">\n                                    <path d=\"M32.4 18 L14.4 0 L10.8 3.6 L25.2 18 L10.8 32.4 L14.4 36 Z\" fill=\"#6D72A2\" fill-opacity=\"0.7\"\/>\n                                <\/svg><br \/>\n                            <\/button><\/p>\n<div class=\"carousel__dots\" id=\"carouselDots\" role=\"tablist\" aria-label=\"Seleccionar diapositiva\">\n                                <!-- Dots inserted by JS so count always matches slide count -->\n                            <\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/div>\n<\/section>\n<p>        <!-- ============================================================\n             3. CAUSES OF XLH\n             ============================================================ --><br \/>\n  <!--      \n\n<section class=\"causes\">\n            \n\n<div class=\"container\">\n                \n\n<h2 class=\"section-heading\">\u00bfCu\u00e1les son las causas de XLH?<\/h2>\n\n\n\n                \n\n<p>\n                    Las personas con XLH tienen una mutaci\u00f3n en el gen <em>PHEX<\/em>, que hace que el organismo\n                    produzca demasiada cantidad de una hormona llamada\n                    <strong>factor de crecimiento de fibroblastos 23 (FGF23)<\/strong>.\n                    El FGF23 controla la cantidad de fosfato presente en la sangre.\n                <\/p>\n\n\n\n                \n\n<ul class=\"causes__list\">\n                    \n\n<li>Un exceso de FGF23 provoca p\u00e9rdida de fosfato a trav\u00e9s de la orina.<\/li>\n\n\n                    \n\n<li>La p\u00e9rdida de fosfato por orina, o con un conductor, conduce a niveles bajos de f\u00f3sforo en la sangre, una condici\u00f3n llamada hipofosfatemia.<\/li>\n\n\n                    \n\n<li>Esto conduce a huesos d\u00e9biles y blandos, la causa subyacente de los s\u00edntomas de XLH.<\/li>\n\n\n                <\/ul>\n\n\n            <\/div>\n\n\n        <\/section>\n\n --><\/p>\n<p>        <!-- ============================================================\n             4. \u00bfPOR QU\u00c9 SE DESARROLLA? \u2014 Genetic inheritance with tabs\n             ============================================================ --><\/p>\n<section class=\"inheritance\">\n<div class=\"container\">\n<div class=\"content-wrap\">\n<h3 class=\"section-heading section-line\">Herencia de XLH<\/h3>\n<p class=\"inheritance__intro\">\n                    <strong>XLH es una enfermedad hereditaria.<\/strong><br \/>\n                    La &#8220;X&#8221; en XLH significa ligado al X, porque la enfermedad se debe a un defecto (una mutaci\u00f3n) en el cromosoma X que se<br \/>\npuede transmitir a los hijos. Los hombres tienen <strong>cromosomas XY,<\/strong> y las mujeres tienen<br \/>\n                    <strong>cromosomas XX.<\/strong>\n                <\/p>\n<p>                <!-- Tabs: Madre con XLH \/ Padre con XLH --><\/p>\n<div class=\"tabs\" id=\"inheritanceTabs\">\n<div class=\"tabs__list\" role=\"tablist\">\n                        <button type=\"button\" class=\"tabs__btn is-active\" role=\"tab\" aria-selected=\"true\" aria-controls=\"panel-madre\" id=\"tab-madre\" data-tab=\"madre\"><br \/>\n                            Madre con XLH<br \/>\n                        <\/button><br \/>\n                        <button type=\"button\" class=\"tabs__btn\" role=\"tab\" aria-selected=\"false\" aria-controls=\"panel-padre\" id=\"tab-padre\" data-tab=\"padre\"><br \/>\n                            Padre con XLH<br \/>\n                        <\/button>\n                    <\/div>\n<p>                    <!-- Tab panel: Madre --><\/p>\n<div class=\"tabs__panel is-active\" role=\"tabpanel\" id=\"panel-madre\" aria-labelledby=\"tab-madre\">\n<div class=\"inheritance__chart\">\n                            <img decoding=\"async\" loading=\"lazy\"\nfetchpriority=\"low\" src=\"https:\/\/www.ultraconecta.com\/ar\/wp-content\/uploads\/madre-con-xlh-v2.png\" alt=\"Gr\u00e1fico explicativo del patr\u00f3n de herencia gen\u00e9tica de XLH\" width=\"937\" height=\"587\">\n                        <\/div>\n<p>                       <!-- \n\n<p class=\"inheritance__caption\">\n                            Si una madre tiene XLH, sus hijos (tanto hijos como hijas) tienen un\n                            50% de probabilidades de tener tambi\u00e9n XLH.\n                        <\/p>\n\n -->\n                    <\/div>\n<p>                    <!-- Tab panel: Padre --><\/p>\n<div class=\"tabs__panel\" role=\"tabpanel\" id=\"panel-padre\" aria-labelledby=\"tab-padre\" hidden>\n<div class=\"inheritance__chart\">\n                            <img decoding=\"async\" loading=\"lazy\"\nfetchpriority=\"low\" src=\"https:\/\/www.ultraconecta.com\/ar\/wp-content\/uploads\/padre-con-xlh-1.png\" alt=\"Diagrama de herencia gen\u00e9tica: padre con XLH, madre sana. Todas las hijas heredan XLH, ning\u00fan hijo var\u00f3n hereda XLH.\" width=\"937\" height=\"587\">\n                        <\/div>\n<p>                       <!-- \n\n<p class=\"inheritance__caption\">\n                            Si una madre tiene XLH, sus hijos (tanto hijos como hijas) tienen un\n                            50% de probabilidades de tener tambi\u00e9n XLH.\n                        <\/p>\n\n -->\n                    <\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/section>\n<p>        <!-- ============================================================\n             5. \u00bfSAB\u00cdAS QUE...? \u2014 Inside the same purple-bg wrapper\n             ============================================================ --><\/p>\n<section class=\"did-you-know\">\n<div class=\"container\">\n<div class=\"content-wrap\">\n<div class=\"did-you-know__card\">\n<h2 class=\"did-you-know__heading\">\u00bfSab\u00edas que&#8230;?<\/h2>\n<p>\n                        <b>Entre el 20% y el 30% de los casos de XLH se consideran espont\u00e1neos.<\/b><br \/>\n                        Esto significa que en algunas personas con XLH, la enfermedad no se hereda de sus padres.<br \/>\n                        Las personas con un caso espont\u00e1neo de XLH pueden transmitir la enfermedad a su descendencia.<br \/>\n                        <!-- El diagn\u00f3stico de las personas con casos espont\u00e1neos de XLH es importante. -->\n                    <\/p>\n<p class=\"did-you-know__cta\">\n                        Si sospech\u00e1s de XLH, consult\u00e1 con tu m\u00e9dico\n                    <\/p>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/section>\n<p>        <!-- ============================================================\n             6. DIAGN\u00d3STICO IS SIMPLE \u2014 Purple card on the same\n                purple-tinted background as the inheritance section above\n             ============================================================ --><br \/>\n       <!-- \n\n<section class=\"diagnosis-band\">\n            \n\n<div class=\"container\">\n                \n\n<div class=\"diagnosis-band__card\">\n                    \n\n<p class=\"diagnosis-band__text\">\n                        El diagn\u00f3stico es sencillo: laboratorio + cl\u00ednica + radiolog\u00eda.\n                    <\/p>\n\n\n                <\/div>\n\n\n            <\/div>\n\n\n        <\/section>\n\n --><\/p>\n<p>        <!-- ============================================================\n             7. ALSO KNOWN AS \u2014 Cyan band with alternate names\n             ============================================================ --><br \/>\n      <!--  \n\n<section class=\"also-known P0 MB35\">\n            \n\n<div class=\"container XLHDiv\">\n                \n\n<h2 class=\"also-known__heading\">XLH tambi\u00e9n puede ser conocida como<\/h2>\n\n\n                \n\n<ul class=\"also-known__list\">\n                    \n\n<li>Raquitismo hipofosfat\u00e9mico ligado al cromosoma X<\/li>\n\n\n                    \n\n<li>Raquitismo hipofosfat\u00e9mico hereditario<\/li>\n\n\n                    \n\n<li>Raquitismo hipofosfat\u00e9mico familiar<\/li>\n\n\n                    \n\n<li>Raquitismo hipofosfat\u00e9mico<\/li>\n\n\n                <\/ul>\n\n\n            <\/div>\n\n\n        <\/section>\n\n  --><\/p>\n<hr class=\"social-resources__divider\">\n<section class=\"references references-main\">\n<div class=\"container\">\n<div class=\"content-wrap-one\">\n<h2 class=\"references__title\">Referencia:<\/h2>\n<ol class=\"references__list\">\n<li class=\"references__item\">\n          Carpenter TO, et al.\u00a0J Bone Miner Res. 2011 Jul;26(7):1381\u20131388.\n        <\/li>\n<li class=\"references__item\">\n         Haffner D, et al. Nat Rev Nephrol. 2019 Jul;15(7):435-455.\n        <\/li>\n<\/ol><\/div>\n<\/p><\/div>\n<\/section>\n<p>        <!-- ============================================================\n             8. FINAL CTA \u2014 Purple band with cyan button\n             ============================================================ --><\/p>\n<section class=\"next-cta MB35\">\n<div class=\"container\">\n<h2 class=\"next-cta__heading\">\n                    <!-- Aprend\u00e9 c\u00f3mo se diagnostica XLH <br \/>--><br \/>\n<span class=\"next-cta__sub_heading\">Hac\u00e9 click ac\u00e1 para saber c\u00f3mo se diagnostica XLH<\/span><br \/>\n                <\/h2>\n<p>                <a href=\"https:\/\/www.ultraconecta.com\/ar\/diagnostico-de-xlh\/\" class=\"btn btn--pill btn--cyan\">Diagn\u00f3stico de XLH<\/a>\n            <\/div>\n<\/section>\n<p>    <\/main><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00bfQU\u00c9 ES XLH? La hipofosfatemia ligada al cromosoma X (XLH) es una enfermedad poco frecuente que afecta a huesos, m\u00fasculos y dientes debido a la p\u00e9rdida excesiva de fosfato. XLH no solo afecta en la ni\u00f1ez. Una persona con XLH convivir\u00e1 con ella durante toda su vida. Paola y Naomi,conviven con XLH Inicio \/ ACERCA [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-123","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u00bfQu\u00e9 es XLH? Hipofosfatemia Ligada al X<\/title>\n<meta name=\"description\" content=\"La Hipofosfatemia Ligada al Cromosoma X (XLH) es una enfermedad rara causada por una mutaci\u00f3n en el gen PHEX, que provoca un exceso de FGF23 y p\u00e9rdida de fosfato. Conozca sus causas, patr\u00f3n de herencia e impacto a lo largo de la vida.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ultraconecta.com\/ar\/acerca-de-xlh\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Qu\u00e9 es la Hipofosfatemia Ligada al X (XLH)?\" \/>\n<meta property=\"og:description\" content=\"La XLH es causada por una mutaci\u00f3n en el gen PHEX que produce exceso de FGF23 y p\u00e9rdida cr\u00f3nica de fosfato, debilitando huesos y m\u00fasculos a lo largo de la vida.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.ultraconecta.com\/ar\/acerca-de-xlh\/\" \/>\n<meta property=\"og:site_name\" content=\"xlh-ar\" \/>\n<meta property=\"article:modified_time\" content=\"2026-09-18T09:11:49+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.ultraconecta.com\/ar\/wp-content\/uploads\/causa-de-xlh-1-1.png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.ultraconecta.com\\\/ar\\\/acerca-de-xlh\\\/\",\"url\":\"https:\\\/\\\/www.ultraconecta.com\\\/ar\\\/acerca-de-xlh\\\/\",\"name\":\"\u00bfQu\u00e9 es XLH? 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